Increase in cases of colorectal cancer among people under 50

Written by Parriva — March 22, 2023
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If you think you’re too young to get colorectal cancer, consider this: About 20,000 people in the U.S. under the age of 50 will be diagnosed this year. And an estimated 3,750 young adults will die.

“Colorectal cancer is rapidly shifting to diagnosis at a younger age,” conclude the authors of an American Cancer Society report released this month. Since the mid-’90s, cases among people under 50 have increased by about 50%. It’s one of the deadliest cancers in this age group.

“The moment that I was diagnosed with colorectal cancer scared me out of my mind,” says Shawna Brown, a union organizer in Stockton, Calif. She was in her late 40s at the time and was completely shocked. “I had no signs or symptoms,” she says.

Brown had received a screening test kit in the mail from her health care provider, but she didn’t think it was urgent and frankly it grossed her out. The test required her to take a stool sample and send it back: “It didn’t seem sanitary,” Brown recalls thinking. “So I ignored the test.” At the time, many people were unaware that in 2018 the American Cancer Society had lowered the recommended age to begin screening from 50 down to 45 years old.
Statistically, people in their 20s and 30s are much less likely to get colorectal cancer compared to people 50 and older, but cases in this age group are rising. They’re expected to increase by 90% by 2030, says Dr. Kimmie Ng, who directs the Young-Onset Colorectal Cancer Center at Dana Farber Cancer Center.

Ng says researchers are evaluating a range of factors that could be fueling the rise in colon cancer, everything from a lack of vitamin D, the complicated role of the microbiome, to the effect of high red meat consumption and the role of diet overall.

A study published in 2021 found that women who drank more than two sugary drinks per day had more than double the risk of early onset colorectal cancer, compared to women who drank less than one drink. And a study published this month suggests people who eat lots of fresh and minimally processed foods are less likely to develop colon cancer, compared to people who consume lots of ultra-processed foods — including processed meats, sweets, carbonated soft drinks and ready-to-eat meals.

And a healthy diet likely plays a role in preventing recurrences among people who are diagnosed with colorectal cancer, a study published in 2019 found. Researchers tracked about 1,000 patients who had been treated for stage 3 colon cancer. They found people who consumed a lot of foods that can spike insulin, such as white bread, sugar-sweetened drinks and processed snacks, were about twice as likely to have a recurrence or die from colon cancer, compared to those who consumed the least of these foods.

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